Breast Cancer Diagnosis

Diagnosing breast cancer follows a step-by-step process designed to identify cancer accurately and guide treatment.

Diagnostic Steps

  • Clinical Breast Exam 
    A healthcare provider examines the breasts and underarms for lumps or other changes.
  • Mammography 
    A mammogram is an X-ray of the breast used to detect abnormalities, often before symptoms appear.
  • Additional Imaging 
    Ultrasound or breast MRI may be used to further evaluate suspicious findings, particularly in people with dense breast tissue or higher risk.
  • Biopsy 
    If imaging shows an abnormal area, a biopsy is performed to remove a small sample of tissue for examination. This is the only way to confirm a breast cancer diagnosis.
  • Pathology Review 
    Pathologists analyze the tissue to determine the cancer type, grade, and whether hormone receptors or HER2 are present.
  • Biomarker Testing 
    Tests such as Oncotype DX may be used after diagnosis to help guide treatment decisions.
  • Genetic Testing 
    Genetic testing (such as BRCA1 or BRCA2) may be recommended for individuals with strong family histories or other risk factors and can be done before or after a cancer diagnosis.

Staging 

Additional tests determine the stage of cancer, including tumor size, lymph node involvement, and whether cancer has spread.

A multidisciplinary team at the GW Cancer Center reviews all findings to create a personalized treatment plan.