Cutaneous T-Cell and B-Cell Lymphoma Symptoms

Cutaneous T-Cell Lymphoma (CTCL)

  • Patches and Plaques: Red, scaly patches that may be itchy, usually appearing on areas of the skin that are not typically exposed to the sun.
  • Tumors: Raised bumps or tumors on the skin, which may ulcerate or become infected.
  • Erythroderma: A severe and widespread reddening of the skin, often accompanied by peeling, itching, and pain.
  • Hair Loss and Nail Problems: Some forms of CTCL can cause changes in the nails or hair loss.
  • Enlarged Lymph Nodes: Swelling of lymph nodes, typically occurring as the disease progresses.

Cutaneous B-Cell Lymphoma (CBCL)

  • Nodules and Tumors: Firm, raised nodules that are red or purple, often located on the head, neck, or trunk.
  • Ulceration: Some of the nodules may develop ulcers.
  • Localized Symptoms: Unlike CTCL, CBCL usually does not cause widespread skin symptoms and is often localized to a few nodules or patches.
  • Rare Systemic Symptoms: CBCL typically does not affect lymph nodes or internal organs, though it can occur in rare cases.

Both types of lymphoma manifest primarily with visible skin symptoms, but systemic involvement can occur, particularly in advanced stages of CTCL. If you or someone you know experiences these symptoms, especially a new growth or a change in an existing skin lesion, it is important to consult a dermatologist for proper diagnosis and management. At the GW Cancer Center, you’ll be seen by doctors and surgeons who rank among the top cutaneous oncology experts in the Washington, DC, region.