Rectal Cancer Treatment

Treatment for rectal cancer typically depends on the stage of the cancer, as well as the patient's overall health and preferences. Here are some common approaches:

  • Surgery: Surgery for rectal cancer depends on the stage and location of the tumor, as well as the patient's overall health. The primary types of surgery performed for rectal cancer include:
    • Local Excision (Transanal Excision): Used for very early-stage rectal cancers, where the tumor is small and has not spread. The surgeon removes the cancer through the anus without making an abdominal incision.
    • Low Anterior Resection (LAR): Commonly used for cancers located in the upper part of the rectum. The surgeon removes the affected part of the rectum and reconnects the colon to the remaining rectum.
    • Abdominoperineal Resection (APR): Used for cancers located in the lower part of the rectum, near the anus. This procedure involves removing the entire rectum and anus, resulting in a permanent colostomy (an opening in the abdomen for waste to exit the body).
    • Proctectomy with Colo-Anal Anastomosis: The rectum is removed, and the colon is directly connected to the anus. This procedure can sometimes be performed with a temporary ileostomy (a small intestine opening) to allow healing.
    • Pelvic Exenteration: A more extensive surgery used for advanced rectal cancers that have spread to nearby organs. It involves removing the rectum and other affected organs, such as the bladder, prostate, or uterus.
    • Minimally Invasive Surgery: Techniques like laparoscopic or robotic-assisted surgery can be used for some rectal cancer procedures, offering smaller incisions and potentially faster recovery times.
  • Chemotherapy
    • Neoadjuvant chemotherapy: Given before surgery to shrink the tumor.
    • Adjuvant chemotherapy: Given after surgery to kill any remaining cancer cells.
  • Radiation Therapy: Sometimes used in conjunction with chemotherapy, especially if the cancer is advanced or has spread to other areas. Radiation can help reduce tumor size and relieve pain or blockages caused by larger tumors.
  • Targeted Therapy: This type of therapy focuses on specific abnormalities within cancer cells. By blocking these abnormalities, targeted therapies can cause cancer cells to die.
  • Immunotherapy: This treatment uses the body's immune system to fight cancer. It's more commonly used for cancers with high levels of certain genetic markers.
  • Palliative Care: Includes treatments to help relieve symptoms and improve quality of life, which can be an important part of managing advanced rectal cancer.

The choice of treatment often involves a multidisciplinary team of specialists, including oncologists, surgeons, radiologists, and gastroenterologists. The treatment plan often involves a combination of these methods and is personalized based on the patient's specific situation, including the cancer stage, location, and the patient's overall health. Regular follow-up and monitoring by your GW Cancer Center team are essential to assess the treatment's effectiveness and manage any side effects or complications.