Pavani Chalasani, MD completed her medical school at Gandhi Medical College in India and completed her Internship, Residency and Fellowship in Hematology-Oncology at the University of Arizona, Tucson. Dr. Chalasani was a part of the University of Arizona Cancer Center (UACC) as a faculty member focusing on breast cancer where she was very active in clinical and translational research.
Her key research interest is in the development of biomarkers- imaging, blood-based or tissue. She is the Principal Investigator on several investigator-initiated, industry-sponsored, and co-operative group protocols. She is the medical oncology study chair on S1706, a NCTN study for patients with inflammatory breast cancer. She was awarded the prestigious NCI’s Clinical Cancer Investigator Team Leadership Award in 2020. She served as Program Director for Hematology-Oncology Fellowship program while at the UACC. She has received research funding from NIH/NCI, American Cancer Society, Better Than Ever and DOD. She was recruited to be Division Director for Hematology-Oncology at the George Washington University, George Washington Cancer Center (GWCC) and started in her new role 02/01/2023. She is also Co-Program Lead for Clinical Translational Oncology Program at GWCC.
A Randomized, Double-blind, Placebo-controlled Phase III Trial Testing Eftilagimod Alpha (soluble LAG-3) in HER2-neg Metastatic Breast Cancer Patients Receiving Paclitaxel, Following an Open-label Dose Optimization
Primary Outcome Measures:
Determination of Overall survival (OS) [Time Frame: Until trial end, death, withdrawal of consent or lost to follow-up, assessed up to 60 months]
Determination of the Optimal Biological Dose (OBD) [Time Frame: Up to 15 months]
Frequency of adverse…
A Phase II Study of the Safety, Tolerability and Antitumor Activity of Tucatinib in Combination With Eribulin and Trastuzumab in Patients With Pretreated Unresectable Locally Advanced or Metastatic HER2+ Breast Cancer
Primary Outcome Measure:
• To assess the safety and tolerability of tucatinib in combination with eribulin and trastuzumab in patients with unresectable or recurrent metastatic HER2+ breast cancer who have had prior treatment with trastuzumab, and trastuzumab deruxtecan.
• Evaluate…
Phase 1 Study of Intratumoral Administration of VAX014 in Subjects With Advanced Solid Tumors
Phase 1 Study of Intratumoral Administration of VAX014 in Subjects With Advanced Solid Tumors