Program Goal
To understand the basic biological processes that underlie cancer progression and interactions with the immune system.
CBIP Specific Aims
- Elucidate the basic mechanisms underlying aberrant DNA damage and repair in cancer and determine therapeutic vulnerabilities
- Discover and integrate signal transduction events regulating tumor-immune cell interactions to expand our understanding of tumor evolution, the immune suppressive tumor microenvironment, and therapy resistance
- Determine the causes and consequences of epigenetic dysregulation in cancer and identify novel epigenetic targets for anti-cancer therapy
CBIP Future Directions
- Release program-specific RFAs with a focus on collaborative team science, thus promoting collaborations within the program
- Facilitate connections with CTOP and CCHE members to create translational research opportunities, enhancing the bench-to-bedside-to-community
- Submit Cancer Biology T32 renewal application in September 2024
