Dr. Jiyoung Lee is an Assistant Professor in the Department of Biochemistry & Molecular Medicine in the School of Medicine and Health Sciences at the George Washington University. After her Bachelor’s and Master’s degree from Korea University, Dr. Lee obtained her Ph.D. degree in the Department of Molecular and Integrative Physiology from the University of Illinois at Urbana-Champaign, and her post-doctoral training in the Ben May Department for Cancer Research at the University of Chicago. Dr. Lee’s research focuses on understanding the molecular mechanism by which metastasis regulators modify gene expression and functional phenotypes including tumorigenesis, metastasis, and metabolism in breast cancer.
Transformed cells adapt metabolism in the microenvironment that has limited nutrients and oxygen to support rapid growth of cancer cells, thus exhibiting distinct metabolic features. Cancer metabolism has contributed to cancer diagnostics as well as therapeutics, which is particularly attractive for the patients who have limited treatment options. Dr. Lee's lab is interested in understanding altered metabolic signatures during tumorigenesis including tumor initiation, growth, and metastasis, and their underlying signaling networks.