Wei Li, PhD, is an Assistant Professor in the Center for Genetic Medicine Research, and a member of the Center for Cancer and Immunology Research at Children’s National Medical Center. He is also an assistant professor of Genomics and Precision Medicine and Pediatrics at the George Washington University.
Dr. Li's laboratory uses the latest genome editing technology (including CRISPR/Cas9 and CRISPR/Cas9 screening) and new computational algorithms to better understand how coding and non-coding elements function especially in human cancer, and to further identify novel molecular targets to inform precision medicine. He is particularly interested in applying new computer science, artificial intelligence and machine learning methods to address challenges in biomedical and biological big data problems. In the past, Dr. Li developed a series of influential algorithms for high-throughput RNA-sequencing and CRISPR/Cas9 based screening (e.g., MAGeCK), and applied them to identify the mechanisms of targeted drug resistance, as well as potential drug targets.