Once completed, the Stem Cell Transplantation and Cell Therapy laboratories will provide a centralized facility and resources for the preparation of therapeutic cellular products.
Services
- Hematopoietic Progenitor Cells (HPC) processing
- CAR-expressing NK- and T-cell preparation
- Antigen-specific cytotoxic T lymphocyte (CTL) generation
- Regulatory T-cell (Treg) expansion
- Clinical grade vector production
Personnel
John Barrett, MD is the medical director of the Stem Cell Transplantation and Cell Therapies laboratories. Dr. Barrett is also a professor of medicine at the GW School of Medicine and Health Sciences and was previously the chief of the Stem Cell Transplantation Section of the Hematology Branch of the National Heart, Lung, and Blood Institute, where he began the stem cell transplant program.
Amarendra K. Neppalli, MD, is the chief of Plasma Cell Disorders and director of Transplant and Cellular Therapy. Dr. Neppalli is also an associate professor of medicine at the GW School of Medicine and Health Sciences.
Eric Yvon, PhD is the laboratory director of the Stem Cell Transplantation and Cell Therapies laboratories. Dr. Yvon is also an associate professor of medicine at the GW School of Medicine and Health Sciences.
Additional personnel include:
- Quality Assurance/Quality Control Director
- Laboratory Supervisor
- Cell Therapy Specialists
Facilities Description
The Stem Cell Transplantation and Cell Therapies Laboratories will be located within Ross Hall at the GW School of Medicine and Health Sciences. The planned design includes a stem cell processing laboratory, two rooms plus anteroom GMP, a quality control laboratory, validated supply room, long-term cell storage room and additional office space.
Goals
The goals of the Stem Cell Transplantation and Cell Therapies Laboratories are to:
- Achieve FACT accreditation
- Provide expertise in the field of cellular therapy to GW investigators
- Foster collaboration in the field of cellular therapy in Washington, D.C. and the surrounding region